More importantly, our study confirms

that there is an int

More importantly, our study confirms

that there is an interaction between two genotypes of CYP1A1 polymorphism find more and smoking. For future studies, strict selection of patients, well-matched controls and larger sample size will be required. Moreover, gene-gene and gene-environment interactions should also be considered. Acknowledgements This work was supported in part by a grant from the Major Program of Nanjing Medical Science and Technique Development Foundation (Molecular Predictor of Personalized Therapy for Chinese Patients with Non-small Cell Lung Cancer) (Lk-Yu). References 1. Alberg AJ, Samet JM: Epidemiology of lung cancer. Chest 2003, 123:21–49.CrossRef 2. Molina JR, Yang P, Cassivi SD, Schild SE, Adjei AA: Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship. Mayo Clin Proc 2008, 83:584–594.PubMedCrossRef 3. Alberg AJ, Brock MV, Samet JM: Epidemiology of lung cancer: looking to the future. J Clin Oncol 2005, 23:3175–85.PubMedCrossRef 4. Rodriguez V, Tardon A, Kogevinas M, Prieto CS, Cueto A, Garcia M, Menendez IA, Zaplana J: Lung

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