As interruption events, we returned to the math tasks Ion Channel Ligand Library clinical trial from Experiments 1–3, but presented

at random locations (as in Experiment 3). A total of 60 students of the University of Oregon participated in exchange for course credits in this experiment. On each trial, four squares (4° side length) were presented at one of four locations, in a crosswise arrangement (8° from the center of the screen). Additionally, a single word (UP, DOWN, LEFT, or RIGHT, presented in 24 point Helvetica font) appeared in the center of one of the squares. Subjects responded with their right-hand index finger by pressing either the 2 (bottom), 4 (left), 6 (right), or 8 (top) key on the numerical keyboard. In the word task, subjects were instructed to press the key that corresponded to the word that was displayed. In the location task, subjects’ key responses were compatible with the spatial location of the word. Each block was 100 trials long. The response–stimulus interval was 1000 ms. The math interruption task was presented exactly as in Experiments 3. Subjects PF-02341066 purchase were randomly selected into the experimental condition or in one of two single-task controls conditions. In the experimental

condition (N = 20), subjects alternated between pure word and pure location blocks. In each of the two control conditions (N = 20), subjects either performed only the word or only the location task throughout the experiment. As in the previous experiments, participants performed on initial practice block for each task that was identical to the following test blocks. We used the same trial exclusion cAMP criteria as in the previous experiments. Initial analyses revealed that in this experiment, different results were obtained for the first vs. the second half of each block. Therefore, Fig. 7 shows the RT and error pattern separated by block half. Given that in this experiment, error patterns could reflect theoretically relevant response-conflict effects, we analyzed them here as well. Turning first to the experimental group, in the first block half there was a clear RT cost-asymmetry pattern,

whereas in the second block half, overall interruption costs and the cost asymmetry pattern were much smaller. In the experimental group, the two-way interaction indicative of the cost asymmetry pattern did not quite reach the significance criterion, F(1, 19) = 3.19, MSE = 3183.20, p > .09; the same is true for the additional modulation of this effect through the response-congruency factor, F(1, 19) = 3.28, MSE = 1224.43, p < .09. However, the cost-asymmetry interaction was significantly modulated through the block-half factor, F(1, 19) = 5.36, MSE = 3466.19, p < .04. In the first half, the cost asymmetry was reliable, F(1, 19) = 6.84, MSE = 2386.41, p < .02, and the additional modulation of this effect by the response-conflict factor was almost reliable, F(1, 19) = 3.83, MSE = 1038.90, p < .07.